We surmise that results obtained from the experiments described in this section cannot serve to understand the role of INaL in arrhythmogenesis.
step one. Van Driessche W, Lindemann B: Focus dependence regarding currents compliment of unmarried salt-selective pores into the frog body. Nature. 1979; 282 (5738): 519-520 PubMed Abstract | Journalist Full Text
It indicates the strong conclusions submit by this manuscript try maybe not justified and i usually do not approve the newest manuscript within means
Brand new article authors provides clarified a number of the questions I increased during the my personal previous review. Unfortuitously, most of the biggest difficulties have not been handled from this modify. When i stated in my personal previous remark, We deem it impractical that all those people affairs are solved simply because of the a few extra paragraphs. As an alternative you may still find some simple inquiries into the experimental design and you can, really vitally, to the research.
It indicates the newest strong findings put https://essayrx.com/write-my-speech/ forward through this manuscript are perhaps not rationalized and i never approve this new manuscript within means
Brand new writers enjoys explained many of the questions We increased inside the my early in the day review. Unfortuitously, all of the major problems haven’t been treated by this update. While i produced in my previous comment, I consider it impractical that those people points will be repaired simply of the a few added sentences. As an alternative there are specific simple inquiries into the experimental design and you will, extremely vitally, with the research.
- The number one issue is if We accompanied the newest malfunction away from the methods in the last adaptation it actually was you’ll be able to to decode, having nearly primary accuracy, one arbitrary stimulus names I chose. Get a hold of to possess samples of which reanalysis. Whether or not i pretend the genuine stimuli checked within an after date or are consistently alternating anywhere between signal and you can quiet, the latest decoding is obviously alongside finest. This really is indicative that the decoding has nothing to complete with the genuine stimuli read by Transmitter but is opportunistically exploiting additional has actually about investigation. This new manage investigation the fresh new writers performed, treating the fresh stimulus labels, you should never target this dilemma because is affected with alike situation. Basically, just what classifier was presumably playing with it’s time who may have enacted given that tape been.
- The reason for this is presumably the article authors utilized non-independent research to possess education and you will evaluation. And when I am aware precisely (select section step three), haphazard sampling half of information samples away from a keen EEG trace aren’t separate data. Repeating the research five times new manage data the people did is not an adequate cure for target it matter. At random seeking examples regarding a time collection that has slow alter (including the slow revolution passion that presumably reigns over this type of tracks lower than these scenarios) commonly usually have solid temporary correlations. Pick TemporalCorrelations.jpg set for 2D occurrence histograms and you may a correlation matrix showing it.
- Because revised steps part will bring increased detail now, they continues to be unclear about what research were utilized. Traditional category study declaration what study has (usual columns in the investigation matrix) and exactly what observations (usual rows) were utilized. Something could well be a feature however, generally speaking this might be this new different EEG streams or fMRI voxels etc. Findings are go out circumstances. Right here I suppose the brand new writers switched the new raw products to the an excellent different room playing with principal role data. This is simply not mentioned in the event the dimensionality is actually smaller with the eigenvalues. Regardless, I assume the knowledge examples (compiled at the 128 Hz) was indeed following made use of just like the findings plus the EEG channels switched because of the PCA were used because the keeps. The latest stimuli labels was indeed tasked given that Towards otherwise Off for each and every shot. A collection of fifty% from products (and you may labels) was then chosen at random to possess knowledge, therefore the other individuals was applied getting assessment. Is it correct?